Basic Information
VIS ID
TVIS20000395
Fusion event
HPV-LOC105375296 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
57211248/57143541 (Hg38)
End
57211248/57143541 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA7A
Target gene
LOC105375296
Nearest miRNA
hsa-mir-1183/Upstream/187677; hsa-mir-10399/Downstream/261484;
Nearest TSS
ENST00000635602/Upstream/3677; ENST00000563054/Downstream/78618;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/123244, chr7-CpG: 22/Downstream/36340
Upstream sequence
gatgcctggggctccatttctgactatgggataatctccaggataaaagccattcattaaagatgctgggacagaaacactggagaaggctaggcgtgga
Downstream sequence
tgtaactatttaccaggacgcacTACCCACCCCGTCTTTCTCtcccacttacttttctgtgctctatacatttttttccagttgtcatttcctgaattgt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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