Basic Information
VIS ID
TVIS20000411
Fusion event
HPV-LOC105375974 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr9
Cytoband
p23
Reference genome
GRCh37/hg19
Start
11289557/11289557 (Hg38)
End
11289557/11289557 (Hg38)
Location type
Intronic
Target gene
LOC105375974
Nearest miRNA
hsa-mir-101-2/Upstream/5281653; hsa-let-7a-1/Downstream/7283749;
Nearest TSS
ENST00000422679/Upstream/13243; ENST00000473763/Downstream/869590;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/676224, chr9-CpG: 37/Downstream/328707
Upstream sequence
AAATAAAGGAAGCCCCGGAGTGGGTATGAGGGATAATGAAGGAGAACTCACAAGAAATGCCCCAGGGCAGAGAGGGAAGCCCCACATTCATCACAGCTGG
Downstream sequence
ATGCATTTCTCATTTTTTCACCTTTAGTTCAAATGTTCTATATTTTCCTTGAAGGATATATTTTCATAAATCCACAAATGCCTACTTCTTTGACTATATG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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