Basic Information
VIS ID
TVIS20000413
Fusion event
HPV-ALOX15P2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr9
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
95679670/92917388 (Hg38)
End
95679670/92917388 (Hg38)
Location type
Intronic
Target gene
ALOX15P2
Nearest miRNA
hsa-mir-101-2/Upstream/389330; hsa-let-7a-1/Downstream/677453;
Nearest TSS
ENST00000422679/Upstream/39350; ENST00000494669/Downstream/30063;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/3897, chr9-CpG: 76/Downstream/141074
Upstream sequence
ACAGGTCAAGTTACAGTAGGCAAGCACGCATAGAAATAAACGTCTAAAACCCAGCCTGTTACATTAGCCAACACTCTTCTTGACTTTTTCCGAATTTTTT
Downstream sequence
TTTATAATATTCTTATCTGACATACCTCACAGAAATGTGATCATGTGCTAAGACCCTAGTAGAGAATCATCATCCTAAAAAATATAAAGATTCCCTCTGT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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