Basic Information
VIS ID
TVIS20000438
Fusion event
HPV-LOC107985698 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chrX
Cytoband
q25
Reference genome
End
127830566/128696588 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7f-2/Upstream/7325535; hsa-mir-105-1/Downstream/5472790;
Upstream sequence
AGCTGAAGGAAAATCTGGATTCAAGGTGTCAGTAATGGTAGTAGTCATAGTAGCAGTAATAAAtgtgtgtgtgtgtgtgtgtgtgtgtgtTTTCAAAATA
Downstream sequence
TGTTTGCTTATGATTAACTTGGTCATGAAAGCTCTTTCCTCTGAGATATTTACTGTGACATGTCATCTATGCTGCTATAATAAACAGTATTCCAACAATT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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