Basic Information
VIS ID
TVIS20000445
Fusion event
HPV-KCTD1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr18
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
24130696/26550732 (Hg38)
End
24130696/26550732 (Hg38)
Location type
Intronic
Target gene
KCTD1
miRNAs that regulate target gene
hsa-mir-196a-5p ; hsa-let-7a-5p
Nearest miRNA
hsa-mir-1-2/Upstream/2228986; hsa-mir-122/Downstream/40735;
Nearest TSS
ENST00000575820/Upstream/913; ENST00000583852/Downstream/78510;
Nearest CpG islands
chr18-CpG: 348/Target, None/Upstream, None/Downstream
Upstream sequence
gagaaaaaacaaattacaaatatcataaatgaaatcactgaaaaacttctataaaagcttaataaagagtagcaacttcatgctagtgactcagacaacc
Downstream sequence
AGGCGTGCTCGTTTCTCCGAGGCTGCGGTGAGCAGCTAAGTTAGTTGCACACTGGGACCCCCACATACGAGCTGGCACACACTAGTCACACACGGCTAAT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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