Basic Information
VIS ID
TVIS20000447
Fusion event
HPV-KCTD1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr18
Cytoband
q11.2
Reference genome
End
24130807/26550843 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1-2/Upstream/2229097; hsa-mir-122/Downstream/40624;
Nearest CpG islands
chr18-CpG: 348/Target, None/Upstream, None/Downstream
Upstream sequence
CTGGACACGTGCAGAAAGGCGTGCTCGTTTCTCCGAGGCTGCGGTGAGCAGCTAAGTTAGTTGCACACTGGGACCCCCACATACGAGCTGGCACACACTA
Downstream sequence
GGCCCTTTGTCCTGGGACGCTCCCAGGTTTTCGGGCCGCGGTGCGGAGAACTCAGGTGGGTGCCCGGCAAGTTACCTACCAGGGGCTGTTCCCCCGCGAC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate