Basic Information
VIS ID
TVIS20000461
Fusion event
HPV-ZMYM5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1;HQ537751.1
Host Sequence
Chromosome
chr13
Cytoband
q12.11
Reference genome
GRCh37/hg19
Start
20402491/19828351 (Hg38)
End
20402491/19828351 (Hg38)
Location type
Intronic
Target gene
ZMYM5
Nearest miRNA
hsa-mir-1267/Downstream/605427;
Nearest TSS
ENST00000623511/Upstream/45332; ENST00000422148/Downstream/13476;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/9784, chr13-CpG: 211/Downstream/34285
Upstream sequence
AGACATCCTCCAAAATGAAATATATATGTTttttaatttttgtggctacataggtgtatatagggcacgtgagatacagacatgtaatgcataataatca
Downstream sequence
catcatgtaaaatggggtatccatcccctcaagcatttatcctttgtgttaAACCTATCTTTAAAAAGAAATTAAAAAAAAACACCATGAAATCTCAATT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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