Basic Information
VIS ID
TVIS20000462
Fusion event
HPV-LOC112268106 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1;HQ537751.1
Host Sequence
Chromosome
chr13
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
88342649/87690394 (Hg38)
End
88342649/87690394 (Hg38)
Location type
Intronic
Target gene
LOC112268106
Nearest miRNA
hsa-mir-1297/Upstream/71654; hsa-mir-1267/Downstream/2540788;
Nearest TSS
ENST00000623511/Upstream/17779; ENST00000430214/Downstream/112970;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/12764, chr13-CpG: 41/Downstream/1672764
Upstream sequence
tcacctgaggtcaggagttcaagaccagcctggccaacatggtgaaaccctgtttctactaaaaatacaaaaattagccaggagtggtggcgcgcacctg
Downstream sequence
taatcccagctactcaggaggctgaggcaggagaatcgcttgaacctgggaggtggaggttgcagtgagctgagatcgtgccattgcactccagcctggg
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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