Basic Information
VIS ID
TVIS20000493
Fusion event
HPV-RP1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1;HQ537751.1
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
55512636/54600076 (Hg38)
End
55512636/54600076 (Hg38)
Location type
Intronic
Target gene
RP1
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-124-1/Upstream/11703801; hsa-mir-10400/Downstream/7114712;
Nearest TSS
ENST00000518652/Upstream/40907; ENST00000220676/Downstream/15991;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/129447, chr8-CpG: 25/Downstream/21167
Upstream sequence
GCAATGACATATTTAAGGTTAAGATCCAAATAGTCTGACACAGAAAATTCCCATCTTGCTCTGTGCTGTGTCTTCGTCCCTTTGGGTGGAGTTCACATGG
Downstream sequence
cttgaattgtagcttccacaattcccacatgttgtaggagggaactggtgggaggtaactgaatgatgagggtgtgtctttcccatgctgttctcgtgac
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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