Basic Information
VIS ID
TVIS20000530
Fusion event
HPV-LINC02547 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr11
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
12076227/12054680 (Hg38)
End
12076227/12054680 (Hg38)
Location type
Intronic
Target gene
LINC02547
Nearest miRNA
hsa-mir-210/Upstream/271458; hsa-let-7a-2/Downstream/109003;
Nearest TSS
ENST00000527297/Upstream/23805; ENST00000476130/Downstream/12249;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/45386, chr11-CpG: 110/Downstream/55586
Upstream sequence
TCAAGGCATACAAATTATGTCTGTCCAAATATAGCTACTTTTGATTTAAACTTTATAACCTGGCTATAGAGTAAGTTTTGTATTCTCATGTTAGATCTTG
Downstream sequence
AGTCAAAATGGTTCTCCTATTAAGGGGTAGAGGATAAGATACCTGAAATAAGGTGTTCTCCTTTCTGTAATCCCTCTCTCCACCTTGGCAGCTTGAAATG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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