Basic Information
VIS ID
TVIS20000546
Fusion event
HPV-LOC105370087 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr12
Cytoband
q24.33
Reference genome
GRCh37/hg19
Start
132173255/131688710 (Hg38)
End
132173255/131688710 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
LOC105370087
Nearest miRNA
hsa-let-7i/Upstream/3394532; hsa-mir-6763/Downstream/893287;
Nearest TSS
ENST00000382841/Upstream/26114; ENST00000535399/Downstream/22371;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/2053, chr12-CpG: 121/Downstream/21779
Upstream sequence
aagggagctgcctggagttcacatagctgtaatccccccggagaaggagccggcactgtgctccaccccatggccagcgcagctacagtgctatgccatt
Downstream sequence
ttggaagtggaactacagctggagtgtcttgtgctaggggagagtagccacttcatccctgagcctaagccaccactgagccacctcagcctagcggccc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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