Basic Information
VIS ID
TVIS20000560
Fusion event
HPV-LOC102724084 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr16
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
80497169/80463272 (Hg38)
End
80497169/80463272 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA16D
Target gene
LOC102724084
Nearest miRNA
hsa-mir-1225/Upstream/3594253; hsa-mir-11401/Downstream/921746;
Nearest TSS
ENST00000527434/Upstream/284143; ENST00000338542/Downstream/77462;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/861632, chr16-CpG: 42/Downstream/77572
Upstream sequence
ttacaaacaatccaattacactattttaattatgaaatatacaattaagttattattgactagaatcaccctgtcattctataaaatagtaggtcttatt
Downstream sequence
CGTTTCTGCTTTAATGTGCATCCTCTGATACAATAATGACTATAGATAATTAGATTAAGTGAAGTTCACCCTTGTCCCAAAACAAGCTTTTTGAGACAGC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate