Basic Information
VIS ID
TVIS20000583
Fusion event
HPV-LOC102724542 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
81968566/81741442 (Hg38)
End
81968566/81741442 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC102724542
Nearest miRNA
hsa-mir-1285-2/Upstream/1874859; hsa-mir-10b/Downstream/4042158;
Nearest TSS
ENST00000437798/Upstream/273974; ENST00000448431/Downstream/264258;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/273885, chr2-CpG: 27/Downstream/2549148
Upstream sequence
cctccagaagtgctgggattacaggcatgagccactgtgctaggcTTAGTCTTTATTAGAGTTCCTAAAGTAACATCTTCTGTTATAAATTGCAAATGAT
Downstream sequence
ATATTTCTAAAGGTTTGGAATAGGGCGAGGAAAGAAGAAATAACTTATACAACAGGAATACTCATAGCCAAAACTACTTATTAATCCTAAATTTAGAGGG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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