Basic Information
VIS ID
TVIS20000669
Fusion event
HPV-LOC101929057 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
GRCh37/hg19
Start
90350829/89641110 (Hg38)
End
90350829/89641110 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA6G
Target gene
LOC101929057
Nearest miRNA
hsa-mir-10398/Upstream/11101801; hsa-mir-1202/Downstream/671632;
Nearest TSS
ENST00000381078/Upstream/2357; ENST00000438877/Downstream/3083;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/2265, chr6-CpG: 52/Downstream/178308
Upstream sequence
GTCTTGAGAAAGGAAAACCAGAAGTAGTTATCACAAATATTACATTACCCTTTCCTAGAAAAAAATGCAATAAAATACTGAAAGAAATCCCTTTGGAATT
Downstream sequence
CATGGAAACACTGGCAGGAATGCTGGGAGAGGAGGGACAGGAGAGTCAAGCAAGAGCCTCACAGGTCACATGAAGAAGCTTGAATATTACCCTCTTCACA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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