Basic Information
VIS ID
TVIS20000724
Fusion event
HPV-LINC01599 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr14
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
50483070/50016352 (Hg38)
End
50483070/50016352 (Hg38)
Location type
Intronic
Target gene
LINC01599
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-208a/Upstream/49841; hsa-mir-1185-1/Downstream/283503;
Nearest TSS
ENST00000550708/Upstream/4963; ENST00000426751/Downstream/22736;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/12651, chr14-CpG: 60/Downstream/99900
Upstream sequence
TAAATTCATCTCACCAATATGGCGCACCTGCAAGTATAATCGTTGTTTTCTTTATTTTCTGCCCTGATGGTTATTTTGTTATCCAGAAGTTTCTTGGACC
Downstream sequence
acagatgtcaaggaattaagactctagattgttggtcggctcattgacctagactctgaaatcccctaaaatcatgacagcagGTGGATTTCACTTCCCT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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