Basic Information
VIS ID
TVIS20000727
Fusion event
HPV-LOC105370982 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
94009998/93466769 (Hg38)
End
94009998/93466769 (Hg38)
Location type
Intronic
Target gene
LOC105370982
Nearest miRNA
hsa-mir-10393/Upstream/562294; hsa-mir-1302-10/Downstream/2866492;
Nearest TSS
ENST00000557528/Upstream/44193; ENST00000554318/Downstream/123098;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/34019, chr15-CpG: 46/Downstream/764617
Upstream sequence
AATATGGGCTACTTTAAAAACTGACATGTATTTGTATACATTCATGCCACAAATATTTATTAAACATCAATAATCAAATTTTAAATCTTAGAAACCCCCA
Downstream sequence
tacacatgaggaaactgagatagagagactttaagtagccaagattacaaagccaatacatggccttcttacaaatgcgtagcatttgtgaaaaaactgc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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