Basic Information
VIS ID
TVIS20000728
Fusion event
HPV-LCMT1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
25134508/25123187 (Hg38)
End
25134508/25123187 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA16E
Target gene
LCMT1
Nearest miRNA
hsa-mir-1225/Upstream/919956; hsa-mir-11401/Downstream/902050;
Nearest TSS
ENST00000527434/Upstream/11255; ENST00000576382/Downstream/16868;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/11066, chr16-CpG: 116/Downstream/134278
Upstream sequence
AAACCAAAAAGAGTCAAGAGAGCAGGAGACAGATTGAAGTGCATCCCTCACTGAAGAGCAAATTTCTTTTCCGTGGTCTGTGCTAGTCTCTTGCAGCAAC
Downstream sequence
ttgatttgagacaacacttgtattatatatAACttctttttttttttttttttttgtgacagagtcttgctctgttgcccaggctagagtgcagtggtgc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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