Basic Information
VIS ID
TVIS20000800
Fusion event
HPV-LOC105373298 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chrX
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
99863590/100608593 (Hg38)
End
99863590/100608593 (Hg38)
Location type
Intronic
Target gene
LOC105373298
Nearest miRNA
hsa-let-7f-2/Upstream/5545367; hsa-mir-105-1/Downstream/6031221;
Nearest TSS
ENST00000429181/Upstream/14969; ENST00000638738/Downstream/28096;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/196367, chrX-CpG: 47/Downstream/27709
Upstream sequence
aagtaactcaggaatgggataccaaacattgtatgttctcactgatacgtgggagctaagctatgagggtgcaaaggcataagaatgatacaatggactt
Downstream sequence
GAATCTTAGGCCAGTAAAAACAAGTTCTATTTTACTGTCACCCAGGGAAATTTCCCTTTTCTTTTGAGTAGACAATAATCCACACTTATTTTTCTAAATC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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