Basic Information
VIS ID
TVIS20000821
Fusion event
HPV-LOC107984447 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr12
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
126601042/126116496 (Hg38)
End
126601042/126116496 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
LOC107984447
Nearest miRNA
hsa-let-7i/Upstream/1200837; hsa-mir-3612/Downstream/2177596;
Nearest TSS
ENST00000382841/Upstream/20488; ENST00000542804/Downstream/51739;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/254662, chr12-CpG: 56/Downstream/74519
Upstream sequence
ggtttgttacataggtaaacacatgtcatggggttttgttgtacatattatttcatcacccaggtgttaagcctagtacccaatagtttactttcctgct
Downstream sequence
cctcaccctcctctcaccctccaccctccaggagaccccagtgtctgtggtttccttctttgtgttcataagttcttatcatttagctcccacttacaag
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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