Basic Information
VIS ID
TVIS20000831
Fusion event
HPV-ZNF609 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr15
Cytoband
q22.31
Reference genome
End
64753233/64461034 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10393/Upstream/590015; hsa-mir-11181/Downstream/301353;
Nearest CpG islands
chr15-CpG: 69/Target, None/Upstream, None/Downstream
Upstream sequence
ggtggtggtgtttttatccattcactagctgatggatatttgggttgtttccagttcttggtgattataaacatgtgcataaaggttcttgtgtgcacat
Downstream sequence
gcgtcgaggggcgcggggTGAAGTTCAAAGCGTGGCCACGGCCGGTTCAGGCTGAGGGTAGGGGTGCCCGGGAGGGGATTAGGGTCTGGCTAGGTTATGG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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