Basic Information
VIS ID
TVIS20000837
Fusion event
HPV-LOC105372529 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr20
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
11308915/11328267 (Hg38)
End
11308915/11328267 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA20B
Target gene
LOC105372529
Nearest miRNA
hsa-mir-103a-2/Upstream/678572; hsa-mir-1-1/Downstream/7142348;
Nearest TSS
ENST00000382410/Upstream/26742; ENST00000450368/Downstream/213380;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/653304, chr20-CpG: 37/Downstream/358607
Upstream sequence
GATGACCGTTGGATACCAGttacacctcttgccccggtgtaattattagtcgtgaccctttcattcccagatatgttccagctggatggcaaattaaaca
Downstream sequence
tagaggatgaaaagaaggaaaagagataagaagggagggaaagaggggaggagaagagcaaaggaaagaggttgggaaggagaggaaagaaaggaggaag
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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