Basic Information
VIS ID
TVIS20000840
Fusion event
HPV-STK32A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr5
Cytoband
q32
Reference genome
GRCh37/hg19
Start
146751762/147372199 (Hg38)
End
146751762/147372199 (Hg38)
Location type
Intronic
Target gene
STK32A
miRNAs that regulate target gene
hsa-mir-1262 ; hsa-mir-1273g-3p ; hsa-mir-4252 ; hsa-mir-4522 ; hsa-mir-4701-3p ; hsa-mir-4793-3p ; hsa-mir-4797-5p ; hsa-mir-5001-3p ; hsa-mir-508-5p ; hsa-mir-542-3p ; hsa-mir-5586-3p ; hsa-mir-5694 ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6849-3p ; hsa-mir-759 ; hsa-mir-766-3p ; hsa-mir-7703 ; hsa-mir-873-3p
Nearest miRNA
hsa-mir-10397/Upstream/3692228; hsa-mir-103a-1/Downstream/1690114;
Nearest TSS
ENST00000502646/Upstream/29726; ENST00000515832/Downstream/10699;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/137118, chr5-CpG: 110/Downstream/80798
Upstream sequence
AATGAAGATTGGAAATTTGAGCTGTAAGTTTCATCAGGTCAGACTTTCTGCAAAGCCTCCTCAGCCTAGGGAGCTAGGCTCATTGAACAGGGACTGGTAT
Downstream sequence
GAGGTCAAAAGTGTATATTGAGTGATGATACAAAACAAGAATGAGGGGCCCAAGAGGAATGGGCTTGGCCtttttttttttttttttttttttttttttt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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