Basic Information
VIS ID
TVIS20000842
Fusion event
HPV-LOC105377742 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537687.1
Host Sequence
Chromosome
chr5
Cytoband
q35.2
Reference genome
GRCh37/hg19
Start
174250145/174823142 (Hg38)
End
174250145/174823142 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
LOC105377742
Nearest miRNA
hsa-mir-10397/Upstream/71355; hsa-mir-1229/Downstream/1544804;
Nearest TSS
ENST00000502646/Upstream/3115; ENST00000507398/Downstream/163153;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/71217, chr5-CpG: 145/Downstream/620608
Upstream sequence
GTCGGAACCTTCCACTGCAGGGCTTCTGGCTGAGATTTTTGGTGCCATCTTCCCTGACCTTTCAGGTTTTTGAGTAGAGAACTGCAATCATTAgccaggc
Downstream sequence
attattttaaagcaaattcaagacatctgaggattccatctgtaaatatgttaataagtgtctctaaaagaggtcatctcattacctccataccattatt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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