Basic Information
VIS ID
TVIS20000871
Fusion event
HPV-C4orf50 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr4
Cytoband
p16.1
Reference genome
End
6012881/6011154 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-378d-1/Upstream/87826; hsa-mir-12113/Downstream/1299296;
Nearest CpG islands
Upstream sequence
aacaaaaattagctgggtgtggtggtgctcgcttgtagttccagctacttgggaggctgaggaggaaggatggcttgagcctcagaggcggaggctgcag
Downstream sequence
CCCCAAATGACCATCTGACCCTGAGGCTTCCCTACTTAAGTCCCCTAAAGCTTGTTCCCCATTGTATTCAGAATTGGGCCATGCAGCGGAGTTGGCCACC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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