Basic Information
VIS ID
TVIS20000888
Fusion event
HPV-LOC105376375 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr10
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
4770143/4727951 (Hg38)
End
4770143/4727951 (Hg38)
Location type
Intronic
Target gene
LOC105376375
Nearest miRNA
hsa-mir-5699/Upstream/736692; hsa-mir-107/Downstream/1424245;
Nearest TSS
ENST00000439456/Upstream/49797; ENST00000525627/Downstream/58678;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/942017, chr10-CpG: 60/Downstream/97982
Upstream sequence
atggtggtgagtgctatggaaaaaaatgaagctgagaaaacagggatggtttagagtggggtttgctattctagaaggatggtcagtgaaagtcttcctg
Downstream sequence
agaagctgatatttaaacaaagacccagagctgagggatggagccctgcaggtctttggATGGGCTAATCTGTTTCAGGAGCTCATTGAATGATACTCCG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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