Basic Information
VIS ID
TVIS20000901
Fusion event
HPV-NCKAP1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
End
183812763/182948035 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-142-3p ; hsa-mir-30a-5p ; hsa-mir-18b-5p ; hsa-mir-132-3p ; hsa-mir-4459 ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-1273e ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-655-5p ; hsa-mir-6087 ; hsa-mir-4537 ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-219b-3p ; hsa-mir-1247-3p ; hsa-mir-6871-5p ; hsa-mir-302f ; hsa-mir-6828-5p ; hsa-mir-922 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-548e-5p ; hsa-mir-6818-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-629-3p ; hsa-mir-498 ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-4284 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1304-3p ; hsa-mir-1281 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-4485-5p ; hsa-mir-6890-3p ; hsa-mir-1200 ; hsa-mir-3653-5p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-660-3p ; hsa-mir-7108-3p ; hsa-mir-4258 ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-576-5p ; hsa-mir-4775 ; hsa-mir-5681b ; hsa-mir-95-5p ; hsa-mir-3163 ; hsa-mir-590-3p ; hsa-mir-3662 ; hsa-mir-4684-5p ; hsa-mir-3675-3p ; hsa-mir-6771-3p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548as-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548c-3p ; hsa-mir-34c-3p ; hsa-mir-1972 ; hsa-mir-383-5p ; hsa-mir-4650-5p ; hsa-mir-4772-5p ; hsa-mir-20a-3p ; hsa-mir-3913-3p ; hsa-mir-4732-3p ; hsa-mir-489-3p ; hsa-mir-544a ; hsa-mir-6719-3p ; hsa-mir-942-5p
Nearest miRNA
hsa-mir-10b/Upstream/1642383; hsa-mir-1244-1/Downstream/1430940;
Upstream sequence
attcagtaggcaggcagctccctagatcccaccgtggtctgcagaggccagcacctgtcccgacctcttactggtcggccctggagagccatctcctaca
Downstream sequence
CATTATACAATTCCAGAAAATGGAATCCTTACAATTAACCTTGTTTTGAAGAACTAAATGATGAAGGCACaatattaaaaatataaatatttCATAGGAA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate