Basic Information
VIS ID
TVIS20000938
Fusion event
HPV-NAA16 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
GRCh37/hg19
Start
41943317/41369181 (Hg38)
End
41943317/41369181 (Hg38)
Location type
Intronic
Target gene
NAA16
miRNAs that regulate target gene
hsa-mir-374b-5p ; hsa-mir-18a-3p ; hsa-mir-155-5p
Nearest miRNA
hsa-mir-2276/Upstream/268081; hsa-mir-1267/Downstream/199105;
Nearest TSS
ENST00000623511/Upstream/6726; ENST00000495148/Downstream/58;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/57121, chr13-CpG: 144/Downstream/87596
Upstream sequence
cttgcctttttcaagtctgctcaaatgtgacttctcaatgaggcggactctgctcactttattatctgttggaaatgcccaccccctagttcttggcatt
Downstream sequence
cccaatcctccttacttgttctatccttgtttaaatccattcatctaatcaccttctcatatactatattgtttacctgttgtgtttgctgtttatggtc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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