Basic Information
VIS ID
TVIS20000947
Fusion event
HPV-GOLGA8DP integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr15
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
23443363/23165653 (Hg38)
End
23443363/23165653 (Hg38)
Location type
Intronic
Target gene
GOLGA8DP
Nearest miRNA
hsa-mir-1268a/Upstream/940324; hsa-mir-10393/Downstream/32174;
Nearest TSS
ENST00000557528/Upstream/28831; ENST00000562295/Downstream/189095;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/125868, chr15-CpG: 56/Downstream/14227
Upstream sequence
GGGCCACATACAAGGTACAGCCACACCCCAGGGTGCTGTCAGAGTCCAGCACTCACAAGTTTACAATGGTTACCCACTTGGTTTCACCTCAGGTCACTGT
Downstream sequence
GCTTGGGGCAAAGCGGTGGCCGAGATGGCCTGCCAAAAGTTGCAGGAGGCCCAGGGGAGGGAGCTGCCGAGGATGGGGCCGTGAGGGGGACGACCTGACA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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