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VISDB
Viral Integration Site DataBase
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TVIS20000975
Basic Information
VIS ID
TVIS20000975
Fusion event
HPV-TSHZ2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr20
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
51981089/53364550 (Hg38)
End
51981089/53364550 (Hg38)
Location type
Intronic
Target gene
TSHZ2
miRNAs that regulate target gene
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-891a-3p
;
hsa-mir-143-5p
;
hsa-mir-5698
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-593-5p
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-6499-3p
;
hsa-mir-767-5p
;
hsa-mir-367-5p
;
hsa-mir-1267
;
hsa-mir-6787-3p
;
hsa-mir-5693
;
hsa-mir-6736-3p
;
hsa-mir-6830-3p
;
hsa-mir-6809-3p
;
hsa-mir-6875-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-4775
;
hsa-mir-6873-3p
;
hsa-mir-6845-3p
;
hsa-mir-942-5p
;
hsa-mir-590-3p
;
hsa-mir-744-3p
;
hsa-mir-4772-3p
;
hsa-mir-1281
;
hsa-mir-6890-3p
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/1911573; hsa-mir-1-1/Downstream/703858;
Nearest TSS
ENST00000382410/Upstream/108571;
ENST00000626626/Downstream/48360;
Nearest CpG islands
None/Target,
chr20-CpG: 39/Upstream/391069
,
chr20-CpG: 26/Downstream/216969
Upstream sequence
ctatgttgcccaggctgggtttgaaggcctgggctcaagcagtcctctcaacttagcttcccaaagtgctgggattacaTGGCACCCAGCCACAAAATTT
Downstream sequence
TTTCTCTTCTTCTGGATGCAAACTGAATGTTGGAAGCATTGCCTTGCAAAGTCAGTAGTCAACAGGGAAGGTTCAGATTTGTTTCTTCCTTGAAAGCTGC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Sample Information
×
Sample name
T2299
Sample type
Tumor
Gender
Female
CpG Island Information
×
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