Basic Information
VIS ID
TVIS20001024
Fusion event
HPV-KIF13B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr8
Cytoband
p12
Reference genome
GRCh37/hg19
Start
29028167/29170650 (Hg38)
End
29028167/29170650 (Hg38)
Location type
Intronic
Target gene
KIF13B
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-124-1/Upstream/665468; hsa-mir-10400/Downstream/786622;
Nearest TSS
ENST00000518652/Upstream/30606; ENST00000521101/Downstream/92412;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/98449, chr8-CpG: 97/Downstream/91790
Upstream sequence
CCATGGACCACCATGCAATTTCTGGAGATGCCGCCTTTGATCCCCTCTTCTCCCTTTGCTCCTCCCTCATCTCCACACTCAAAGTGCACATTATTCAGAT
Downstream sequence
TAAAGTCCTAGAGGCAAGACAACACTCATCACTTAGCTGGAATTTGTAACACCAAGAAGCACAagatgaacaataaaaaaagtaaaaggggtcagctcat
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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