Basic Information
VIS ID
TVIS20001032
Fusion event
HPV-LOC728877 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr9
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
69234037/63990621 (Hg38)
End
69234037/63990621 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA9F
Target gene
LOC728877
Nearest miRNA
hsa-mir-101-2/Upstream/22756786; hsa-let-7a-1/Downstream/6819354;
Nearest TSS
ENST00000422679/Upstream/176462; ENST00000615302/Downstream/378773;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/130559, chr9-CpG: 29/Downstream/30503
Upstream sequence
TTATCTGCCAGACTCCAGATAAGAAACAGGAAATGAGAATAGAAGAGACCAGTGATTTGTCTGAAGAGTGGGTGGAAGACCCAGAAGACTGCCCAAGGGA
Downstream sequence
gaccctcttcccattgagaggtggggtctctaccccttacccACACtgaccctcttcccattgagaggtggggtctctaccccttacccACACtgaccct
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate