Basic Information
VIS ID
TVIS20001039
Fusion event
HPV-LOC100130724 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chrX
Cytoband
q12
Reference genome
GRCh37/hg19
Start
65040981/65821139 (Hg38)
End
65040981/65821139 (Hg38)
Location type
Intronic
Target gene
LOC100130724
Nearest miRNA
hsa-let-7f-2/Upstream/2035052; hsa-mir-105-1/Downstream/197731;
Nearest TSS
ENST00000429181/Upstream/153469; ENST00000424241/Downstream/178612;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/153169, chrX-CpG: 45/Downstream/915
Upstream sequence
CCAGAAAGAAATCCAGGTCTTCCAGTCAGTCAGTGTCTTCCAGAAAAATCTACGTCTTCCACCAAATCCAGGTCTTCCAGTCAATCCACATCTTCCGGAA
Downstream sequence
CTTTGTAGATAAAGGTCCTGTGACGTTATAACCCCTCATTTCTCCCTTTAAGAGAGGATGGCTTTAGAGTGCTGAATACCAATGAAGTCATCAGTGCTGA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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