VISDB Viral Integration Site DataBase

VIS ID

TVIS20001055

Fusion event

HPV-NRAS integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Not given

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HPV

Reference genome

NC_001526.2;HQ537777.1

Chromosome

chr1

Cytoband

p13.2

Reference genome

Start

End

115257481/114714860 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-mir-20a-5p ; hsa-let-7c-5p ; hsa-mir-145-5p ; hsa-mir-148b-3p ; hsa-mir-124-3p ; hsa-mir-98-5p ; hsa-mir-877-3p ; hsa-mir-214-3p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-523-5p ; hsa-mir-518f-5p ; hsa-mir-526a ; hsa-mir-520c-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-522-5p ; hsa-mir-519a-5p ; hsa-mir-4686 ; hsa-mir-2681-5p ; hsa-mir-2113 ; hsa-mir-3123 ; hsa-mir-3925-5p ; hsa-mir-4468 ; hsa-mir-543 ; hsa-mir-4480 ; hsa-mir-2276-3p ; hsa-mir-4772-3p ; hsa-mir-7109-3p ; hsa-mir-3662 ; hsa-mir-513a-5p ; hsa-mir-1193 ; hsa-mir-3613-3p ; hsa-mir-2392 ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-6833-5p ; hsa-mir-218-5p ; hsa-mir-8068 ; hsa-mir-3190-3p ; hsa-mir-3650 ; hsa-mir-6077 ; hsa-mir-2467-3p ; hsa-mir-7-5p ; hsa-mir-7114-5p ; hsa-mir-4257 ; hsa-mir-548b-3p ; hsa-mir-1303 ; hsa-mir-3143 ; hsa-mir-4537 ; hsa-mir-520g-5p ; hsa-mir-2278 ; hsa-mir-219b-3p ; hsa-mir-922 ; hsa-mir-92b-3p ; hsa-mir-367-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-5585-3p ; hsa-mir-3160-5p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-4774-5p ; hsa-mir-4490 ; hsa-mir-4719 ; hsa-mir-425-5p ; hsa-mir-944 ; hsa-mir-26a-5p ; hsa-mir-181a-5p ; hsa-mir-98-3p

Nearest miRNA

hsa-mir-101-1/Upstream/1832731; hsa-mir-1182/Downstream/1845164;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/44496, chr1-CpG: 35/Downstream/65594

Nearest cancer related gene

NRAS(OG, No orient, 0)

Upstream sequence

cgagccatcatacccagccaatttttgtatttttagtagagacagggttttgccatgttggccaggctggtttcaaactcctgacctcaagtgatccacc

Downstream sequence

cacctaggcctcccaaagtgctgggattatgggagtgagcaaccacgcccagccTGTATTTCACAATCTCCAGTTTCTTTGAGGTCCACAGACCTTTTGC