Basic Information
VIS ID
TVIS20001059
Fusion event
HPV-LOC112268276 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr1
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
166166515/166197278 (Hg38)
End
166166515/166197278 (Hg38)
Location type
Intronic
Target gene
LOC112268276
Nearest miRNA
hsa-mir-101-1/Upstream/42480; hsa-mir-1182/Downstream/1801382;
Nearest TSS
ENST00000473358/Upstream/30309; ENST00000425271/Downstream/137606;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/30067, chr1-CpG: 112/Downstream/641826
Upstream sequence
ATCTGATATTCATTAGATGCCACTTCAAATTCCTACTAAGGAggaagggaagggaagggaagggaagggaaggcaacagcaaagaagaaaagggaagagt
Downstream sequence
aaaggaggggagggaaagaaaATAGAAAAATTTTAGAGTCCACCCTTTCATTTTATAACAATCAGTAAAGTTTATTTTTTTACTGGGATAAAGACATTAT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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