Basic Information
VIS ID
TVIS20001067
Fusion event
HPV-CD55 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr1
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
207496609/207323264 (Hg38)
End
207496609/207323264 (Hg38)
Location type
Intronic
Target gene
CD55
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-let-7a-5p ; hsa-mir-4760-3p ; hsa-mir-7977 ; hsa-mir-6516-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-4278 ; hsa-mir-542-3p ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-4489 ; hsa-mir-664b-5p ; hsa-mir-4645-3p ; hsa-mir-5697 ; hsa-mir-3938 ; hsa-mir-664a-3p ; hsa-mir-656-3p ; hsa-mir-6732-5p ; hsa-mir-6805-5p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-190a-3p ; hsa-mir-340-5p ; hsa-mir-6853-3p ; hsa-mir-5011-5p ; hsa-mir-5590-3p ; hsa-mir-410-3p ; hsa-mir-142-5p ; hsa-mir-1277-5p ; hsa-mir-548m ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-4752 ; hsa-mir-6833-5p ; hsa-mir-4753-3p ; hsa-mir-3190-3p ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-627-3p ; hsa-mir-130b-5p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-548c-3p ; hsa-mir-3692-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-3144-3p ; hsa-mir-1252-5p ; hsa-mir-942-5p ; hsa-mir-136-5p ; hsa-mir-6884-3p ; hsa-mir-875-5p ; hsa-mir-6813-3p ; hsa-mir-3200-3p ; hsa-mir-6809-3p ; hsa-mir-4799-5p ; hsa-mir-34b-3p ; hsa-mir-4776-3p ; hsa-mir-192-3p ; hsa-mir-5189-3p ; hsa-mir-532-5p ; hsa-mir-651-3p
Nearest miRNA
hsa-mir-101-1/Upstream/848400; hsa-mir-1182/Downstream/478588;
Nearest TSS
ENST00000473358/Upstream/1473; ENST00000488171/Downstream/1394;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1245, chr1-CpG: 72/Downstream/130922
Upstream sequence
cttatgtaaattgctcaataaatcaaacatttaaaaaTATTTAATTAAAATATTAAACATTTCATGTAAAATATTAAAGCTGTTAAGCTCAAAATAAAGA
Downstream sequence
TTTTGCCAAGGGTTAGCAACCAATTTTTTATAGTGGCTACATTAGAGTTAGTTTTCATCAATTAAACACGAGTAGCCAGATGGTAGGGAGGCCAGGTGTT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate