Basic Information
VIS ID
TVIS20001112
Fusion event
HPV-LOC107984330 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr11
Cytoband
p11.12
Reference genome
GRCh37/hg19
Start
50229053/50269882 (Hg38)
End
50229053/50269882 (Hg38)
Location type
Intronic
Target gene
LOC107984330
Nearest miRNA
hsa-mir-129-2/Upstream/2173024; hsa-let-7a-2/Downstream/6473991;
Nearest TSS
ENST00000527297/Upstream/287347; ENST00000525654/Downstream/28697;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1727, chr11-CpG: 18/Downstream/8955
Upstream sequence
TGTTAATAACCAACTGTGTCTGATCCGAAATTTGCTGTCCCATGATGAAAAGATGTCTTTCAAAATCCAGAGTGTTGCTTCACATAGTTTCTGTCAAATA
Downstream sequence
TACAGAAAAGTTACTTTTACATATTATACAAAAACGGCAATATACTCATTCTTCAAAAACATAAAGAAAAACTAGGGATACCTTTAAGTGAGAGTTGAGT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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