Basic Information
VIS ID
TVIS20001116
Fusion event
HPV-ARHGAP20 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr11
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
110515054/110644331 (Hg38)
End
110515054/110644331 (Hg38)
Location type
Intronic
Target gene
ARHGAP20
Nearest miRNA
hsa-mir-10392/Upstream/6794351; hsa-let-7a-2/Downstream/703426;
Nearest TSS
ENST00000527297/Upstream/54646; ENST00000635886/Downstream/67719;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/213721, chr11-CpG: 197/Downstream/66785
Upstream sequence
tgcctcttttagtgacatacagttaagaccaggcactgtgagtactcagctgatttttggtctttatgaaggtgctttgttatgtgtgtagatagttgtt
Downstream sequence
aaattggtgtccttgctgggggaagatcagtgtagccttttttccggccatcttgttccaccCTTTGGtctactcttttggcattttttaagaatacagt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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