Basic Information
VIS ID
TVIS20001130
Fusion event
HPV-LOC100506869 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
59181560/58787778 (Hg38)
End
59181560/58787778 (Hg38)
Location type
Intronic
Target gene
LOC100506869
Nearest miRNA
hsa-mir-1228/Upstream/963086; hsa-let-7i/Downstream/3472581;
Nearest TSS
ENST00000382841/Upstream/6031; ENST00000548969/Downstream/12594;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/851557, chr12-CpG: 100/Downstream/132000
Upstream sequence
tttctctttcttttcttgtctttccctccctccctctctctttcttccttcctctcctctcccttccctttccttccttccctttccttccctccctccc
Downstream sequence
tccctccctccctcccttccttccttccttccttccttccttccttccttccttcTCTCTCTCtttctttctttctttctttttctttcttctcgctctg
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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