Basic Information
VIS ID
TVIS20001131
Fusion event
HPV-GRIP1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr12
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
67036175/66642395 (Hg38)
End
67036175/66642395 (Hg38)
Location type
Intronic
Target gene
GRIP1
Nearest miRNA
hsa-let-7i/Upstream/391238; hsa-mir-1178/Downstream/2630762;
Nearest TSS
ENST00000382841/Upstream/71337; ENST00000539109/Downstream/4954;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/406771, chr12-CpG: 105/Downstream/426495
Upstream sequence
gctgggattacaggtgtgagccaccgtgcctggccACCAAAATATTTTTTTAAGAGAgtgagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgGAGGTTGT
Downstream sequence
TTACTCATTGCAAGATATAAAAAAAGGAAGTGGTACCAATACCACCCATataggcaaaatggactacattaaaatttaaaacttctgtgcatcgaagagc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate