Basic Information
VIS ID
TVIS20001134
Fusion event
HPV-LTA4H integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
End
96411603/96017825 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7i/Upstream/707841; hsa-mir-1178/Downstream/1474084;
Upstream sequence
TGCGTCCACAAAGTCAAGGGGAAATATTCACCTGTTGTTAACTTAATTTGTATATGAGATGTTAACCAAATGTTGGGGCTAAATTGCAGTAGATGTGTTA
Downstream sequence
CTTATTGTTGTAAGCGCCTAGGGTAATATTTATATCCCTTGAGTTTGGCTGCTTTTTTTAATCAAATCTCTTTTCCCCACTTTTTCATTGTTTCACTCAT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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