Basic Information
VIS ID
TVIS20001164
Fusion event
HPV-LOC105370765 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh37/hg19
Start
35388496/35096295 (Hg38)
End
35388496/35096295 (Hg38)
Location type
Intronic
Target gene
LOC105370765
Nearest miRNA
hsa-mir-1233-1/Upstream/567924; hsa-mir-10393/Downstream/275961;
Nearest TSS
ENST00000557528/Upstream/11185; ENST00000560866/Downstream/73403;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/3090, chr15-CpG: 36/Downstream/25586
Upstream sequence
catgatctacctgcctcggcctcccaaagtgctgggattacaggcatgagccaccgtgcccagccacacacatgattttatataactgtttgtttacatg
Downstream sequence
AGGAGAAGAGGGAGATTCCTAGAGAAAAAAGGGAAGCACAGAATCAGCAGCCTCTACCTTCCAAAAACATTTCAAAAATCACTCTACCCATCAGGAGGAT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate