Basic Information
VIS ID
TVIS20001173
Fusion event
HPV-LOC105371082 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr16
Cytoband
p13.13
Reference genome
GRCh37/hg19
Start
11454162/11360305 (Hg38)
End
11454162/11360305 (Hg38)
Location type
Intronic
Target gene
LOC105371082
Nearest miRNA
hsa-mir-1225/Upstream/53778; hsa-mir-11401/Downstream/1360016;
Nearest TSS
ENST00000527434/Upstream/10984; ENST00000572950/Downstream/23400;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/14395, chr16-CpG: 31/Downstream/133458
Upstream sequence
TGTTAATGACCCAAGAATGCATCCAAAGGGGTTACATGCAAACCTGCCTGAGCATGGAAGATCAGTCTTGAGTGCTTTATTAAGTCTGGCTCTATCAAAG
Downstream sequence
tgtatccaacgggttggaatcgtgtctgtggaggggaaggggtatcttagaattctgtccacGAGGACCTGCCTGATGGaacagcacaatagggcttcag
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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