Basic Information
VIS ID
TVIS20001177
Fusion event
HPV-TMEM219 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
29977770/29966449 (Hg38)
End
29977770/29966449 (Hg38)
Location type
Intronic
Target gene
TMEM219
Nearest miRNA
hsa-mir-1225/Upstream/367184; hsa-mir-11401/Downstream/537470;
Nearest TSS
ENST00000527434/Upstream/3033; ENST00000566552/Downstream/7192;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/4200, chr16-CpG: 73/Downstream/6894
Upstream sequence
TGGCTTGCATTAGGGACTGCAGAGTGTGAAGGTGCCTAGTGAAAAGCCAGTAAGGTCATAACCATTAGAATAGGTAGTATCAGCCAGCCGGGCATGGTGG
Downstream sequence
atcactcttgtcctttattaaaacttttaggttttgtgtctttcataggaagcccttcctcattttaaaattagaaaatattctggccaggcgtggtggc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate