Basic Information
VIS ID
TVIS20001184
Fusion event
HPV-PIK3R5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
8847371/8944054 (Hg38)
End
8847371/8944054 (Hg38)
Location type
Intronic
Target gene
PIK3R5
Nearest miRNA
hsa-mir-1253/Upstream/757050; hsa-mir-10226/Downstream/3137845;
Nearest TSS
ENST00000595228/Upstream/31537; ENST00000585297/Downstream/21561;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/55367, chr17-CpG: 81/Downstream/21098
Upstream sequence
CTTTTTGCTTAATTTTTGGAATACTCTGGCATCTGTTACATTATAGGAGAGACATCCAGGAGACAGCAAAAACTATAATGAATGTATCCGGCACGAGACC
Downstream sequence
caagtaagccccagtgtctgttggtcctttctttgtgtccatgagttctcatcatttagttcccacttataagtgagagcatgtattttgtcttctgttc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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