Basic Information
VIS ID
TVIS20001197
Fusion event
HPV-LOC105371984 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr18
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
10091312/10091315 (Hg38)
End
10091312/10091315 (Hg38)
Location type
Intronic
Target gene
LOC105371984
Nearest miRNA
hsa-mir-3976/Upstream/3716890; hsa-mir-1-2/Downstream/668269;
Nearest TSS
ENST00000575820/Upstream/143721; ENST00000582470/Downstream/34025;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/58405, chr18-CpG: 31/Downstream/40541
Upstream sequence
CGGGCCTGGAAACTACAAAGGATTGTGTTAATTTTGTGTTTAggaagaaagaggtaatgggtaggaatcaatgtaaacttattcataggccacaccaaac
Downstream sequence
taccactccgtggcctgttaggaaccaagccgcacagcaggaggtgagcagcaggagagcaagcaaagcttcatctgcattcatagctgctcccctcccc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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