Basic Information
VIS ID
TVIS20001209
Fusion event
HPV-MARCH2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
End
8499219/8434335 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1227/Upstream/44955; hsa-let-7e/Downstream/1604019;
Upstream sequence
TCTGCCCAGTGGCCTTGGGAGAACGGAACCGCCCTGGCCGTCCAGCCCAGCCCTGTCTCCCTGCCAGCCGCGCACAGGCTGTCCCCGGCATGTCCCAGGA
Downstream sequence
ggccttccaaagtgctgagattacaggcatgaaccatcgcgccctgccCCTACCAGCATATTTTAAAATATGTAAATAGGATGAAATCATAGCTACTGTT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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