Basic Information
VIS ID
TVIS20001244
Fusion event
HPV-LOC107985988 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr2
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
221762200/220897480 (Hg38)
End
221762200/220897480 (Hg38)
Location type
Intronic
Target gene
LOC107985988
Nearest miRNA
hsa-mir-10b/Upstream/990915; hsa-mir-1244-1/Downstream/4112981;
Nearest TSS
ENST00000437798/Upstream/106402; ENST00000609776/Downstream/528060;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1269415, chr2-CpG: 260/Downstream/673530
Upstream sequence
tcctgaggtgacctacatcctcagcttacgaagataataggattaagagactaaagtaaaggcaggcataagaaattataaaagtattatttgagaactg
Downstream sequence
GAAACTTTGCTGAGTCCCAACCATGCTCCTACTCCTCCTTGGGACACAGCaatgaggcaatgcagagagagatccatgagtgcagagtcagacttcccat
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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