Basic Information
VIS ID
TVIS20001298
Fusion event
HPV-LOC105377509 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr4
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
158908499/157987347 (Hg38)
End
158908499/157987347 (Hg38)
Location type
Intronic
Target gene
LOC105377509
Nearest miRNA
hsa-mir-12113/Upstream/5450831; hsa-mir-1305/Downstream/1141455;
Nearest TSS
ENST00000502981/Upstream/349660; ENST00000514381/Downstream/172334;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/764446, chr4-CpG: 20/Downstream/223009
Upstream sequence
gttggccaggatggtcttcatctcctgacctcgtgatctgcccgcctcggcctcccaaagtgctgggattacaggcgtgagccactgcaccccaccctgt
Downstream sequence
AACTACTTACAGGAGGGTGAAAATCTGTAACACATAAAAGAGCCTAACTTTTAAGAATTACAGTCAACATGATGTTGAATAACATAAAAATGTAAAGATC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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