Basic Information
VIS ID
TVIS20001312
Fusion event
HPV-PDE4D integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr5
Cytoband
q12.1
Reference genome
End
59633900/60338073 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/634370; hsa-mir-103a-1/Downstream/11831394;
Upstream sequence
GGGCGGGCGGCGGGTTGTCTCCCCTGCCAAAGCTCTGGTTTCTGGAGAGGTGAGAGGAATTGGAGGAGTTAGTGTTGTTTCTTTTGAGAGTGGTGGCCTG
Downstream sequence
TATATAGGTAGATAAAGGAAGGTGAGTAGCCGGAGAAAAAAGGCAGACGATCAGCTGCACAGGTGGGTCAGCACAAACGATGAAAGCCGTTGACACTCAG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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