Basic Information
VIS ID
TVIS20001320
Fusion event
HPV-LOC105377703 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
GRCh37/hg19
Start
163757887/164330881 (Hg38)
End
163757887/164330881 (Hg38)
Location type
Intronic
Target gene
LOC105377703
Nearest miRNA
hsa-mir-10397/Upstream/3845431; hsa-mir-103a-1/Downstream/3834964;
Nearest TSS
ENST00000502646/Upstream/33752; ENST00000519901/Downstream/23259;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/824941, chr5-CpG: 17/Downstream/2647598
Upstream sequence
CAGAATGTACAAAATGGGTCAAAAAAGTGTGGCCAGTCTAAAACTGAAAAGACAAGTCAGGTAAAAAAGCAAATGGAAGCAGTAATCAGAATTTAAAATG
Downstream sequence
tcctgtgaccatgaagggagagaccaagggaatgagagaaacacatggaggtgaaaagagtttagccaggagagagtctggatcctggcaacaatgtcta
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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